Starting Suboxone | MyStreetHealth

Starting treatment

Buprenorphine is started once withdrawal begins.

Suboxone (buprenorphine/naloxone) is started after opioids have begun to clear from the body and withdrawal symptoms are present.

Starting too early can cause precipitated withdrawal — a sudden worsening of symptoms. Your physician will guide you on when to take your first dose.

Timing

Timing depends on the opioid used.

Short-acting opioids (heroin, oxycodone, hydrocodone) typically require 6–24 hours after the last use — once mild to moderate withdrawal is present.

Longer-acting opioids (methadone, extended-release formulations) may require 24–72 hours or more. Fentanyl can behave differently due to tissue accumulation — your physician will assess this at your first visit.

Do not start buprenorphine until you are in withdrawal. Your physician will confirm timing with you during your visit.

Your first visit

What happens at your first appointment.

1

Call or text

Same-day visits often available. No referral needed. (888) 835-9995.

2

Medical evaluation

Your physician reviews your history, current opioid use, and any relevant health conditions. A real clinical evaluation — not a checklist.

3

Induction plan

Your physician determines the right starting dose and walks you through exactly when and how to take your first dose. You leave with clear instructions.

4

Ongoing care

Same physician every visit. Monthly appointments once stable.

What to expect

The first few days.

Many patients notice a reduction in withdrawal symptoms within the first few hours after the initial dose. The goal is comfort — not sedation.

Dose adjustments are common in the first week. Your physician will work with you to find a dose that controls withdrawal and cravings without side effects.

Where we practice

Virginia · Maryland · Washington DC · West Virginia · Ohio

Starting Suboxone.